According to a population-based study, it is estimated that 7.1% of Koreans experience GERD symptoms at least once a week.9 Although GERD prevalence in Korea is relatively lower than that in Western countries with the symptomatic prevalence of 20C25%,10 the disease has been regarded as an important health problem even in Korea because of the enormous nationwide cost of medication and poor QOL of GERD patients. Since the indication of anti-reflux surgery for GERD is established well in Western countries, laparoscopic anti-reflux surgery is the most common surgical procedure for upper gastrointestinal tract diseases. in 45.5% and partially controlled in 36.4%. GERD-related QOL scores at 1 week Dehydroepiandrosterone after surgery Dehydroepiandrosterone significantly improved compared with pre-operative scores. There was no difference in GERD-related QOL scores between 1 week and 3 months after surgery. General QOL measured with European QOL-5 sizes and health-related QOL instrument with 8 items significantly improved after anti-reflux surgery. Satisfaction with treatment was significantly higher after surgery than before surgery (72.5% vs 11.8%, 0.001). Conclusion Anti-reflux surgery improved GERD symptoms and QOL in patients. Anti-reflux surgery is an effective treatment option compared with medical treatment for GERD patients selected for surgical treatment. test. Statistical analysis was performed using SPSS version 19.0 (IBM Corp, Armonk, NY, USA). Results Patient Characteristics The baseline characteristics for patients are outlined in Table 1. Of the 51 patients who underwent anti-reflux surgery between February and October 2018, 31 were male and 20 were female. The mean age was 53.3 PVRL1 years. Most patients were in their 50s (31.4%), and 17.6% patients were elderly aged over 70 years. There were 31 (60.8%) patients with normal body weight, 2 (3.9%) were underweight, and 18 (35.3%) were overweight; no patient experienced a BMI above 30, and thus, there were no cases of obesity. Table 1 Patient Demographics and Characteristics = 0.227 and = 0.791; Table 6). Table 6 Post-operative Adverse Symptoms 0.001), and there was no switch between 1 week and 3 months. Table 7 Quality of Life Results Before and After Anti-reflux Surgery test. GERD, gastroesophageal reflux disease; EQ-5D, European quality of life-5 sizes; HINT-8, health-related quality of life instrument with 8 items. Data are shown as the mean SD. The questionnaire experienced one simple question asking whether the individual was satisfied with the current treatment, indicating individual satisfaction with medical treatment before surgery and with antireflux surgery after surgery (Physique). Dehydroepiandrosterone Although only 11.8% were satisfied with the medical treatment before surgery and 51.0% were dissatisfied with treatment at that time, 72.5% and 73.0% were satisfied with treatment at 1 week and 3 months after surgery, re-spectively. Satisfaction with treatment was significantly higher after surgery than before surgery ( 0.001, McNemar test), and there was no significant difference between 1 week and 3 months after surgery (= 1.000, McNemar test). Open in a separate window Figure Satisfaction with current treatment for gastroesophageal reflux disease (for medical treatment before surgery (pre-operative) and 1 week and 3 months after anti-reflux surgery (1 wk and 3 mo, respectively). General quality of life The EQ-5D QOL value was 0.72 0.02 (mean SE) before surgery, 0.83 0.02 at 1 week after surgery, and 0.89 0.02 at 3 months after surgery. The QOL value measured by HINT-8 was 0.75 0.01 before surgery, 0.84 0.01 at 1 week after surgery, and 0.87 0.01 at 3 months after surgery (Table 7). Both steps of general QOL were increased at 1 week postoperatively compared with pre-operative steps ( 0.001). EQ-5D value continued to increase at 3 months (= 0.008) compared with 1 week after surgery, whereas HINT-8 values remained unchanged. Conversation Dehydroepiandrosterone The prevalence of GERD has substantially increased in a few recent decades.8 This has been a common pattern both in the Western countries and in Korea, making GERD one of the most common chronic benign diseases. According to a population-based study, it is estimated that 7.1% of Koreans experience GERD symptoms at least once a week.9 Although GERD prevalence in Korea is relatively lower.